The Effect of Eight Weeks of Resistance Training and Testosterone Enanthate Consumption on TNF-α and IL-6 Genes’ Expression in the Kidney Tissue of Female Wistar Rats

Objectives: This study aimed to evaluate the effect of a testosterone enanthate anabolic steroid on gene expression inflammatory factors in kidney tissue female rats following eight weeks resistance training. Methods: Twenty-one Wistar weighing 200 ± 20 g, aged weeks, were prepared from Iran Pasture Institute. Following week for acclimatization, randomly divided into three groups: control (n = 7), training + placebo 6), and 8). Resistance included five days climbing 1-meter ladder with 26 stairs while bearing weights two rest. In first week, equal 40% rats’ body weight. weight was increased by 20% per week. The weighed times group, injected mg thrice Forty-eight hours last session injection, samples collected determine interleukin-6 (IL-6) tumor necrosis factor-alpha (TNF-α) using real-time PCR. Results: results showed that consumption significantly TNF-α IL-6 undergoing (P 0.001). Conclusions: findings this demonstrated all rats.